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Science Backed Benefits of Dragon's Blood​

 

1. Dragon’sBlood Cream & Human Wound Healing (Clinical Trial)

Namjoyan F, et al. Efficacy of Dragon's blood cream on wound healing: A randomized, double-blind, placebo-controlled clinical trial.
Journal of Traditional and Complementary Medicine (2015)
Link: https://pmc.ncbi.nlm.nih.gov/articles/PMC4737969/

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2. Wound-Healing Activity of Croton lechleri (Animal Study)

Pieters L, et al. In vivo wound healing activity of Dragon's blood (Croton lechleri). Planta Medica.
Link: https://europepmc.org/article/med/23196095

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3. Botany, Chemistry & Therapeutic Uses (Comprehensive Review)

Gupta D, et al. Dragon's blood: botany, chemistry and therapeutic uses.
Journal of Ethnopharmacology (2008)
Link: https://www.sciencedirect.com/science/article/abs/pii/S0378874107005387

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4. Antioxidant & Nutraceutical Potential of Dragon’s Blood

Peres ISA, et al. Dragon’s Blood: antioxidant properties for nutraceuticals and pharmaceuticals.
Rendiconti Lincei (2023)
Link: https://link.springer.com/article/10.1007/s12210-022-01122-4

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5. Pharmacology of Croton lechleri (Modern Review)

de Albuquerque RDDG, et al. Pharmacology of Croton lechleri Muell. Arg.
Planta Medica (2025)
Link: https://www.thieme-connect.com/products/ejournals/html/10.1055/a-2551-5681

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6. Chemical Constituents & Pharmacological Properties of Dracaena cinnabari

Vaseem M, et al. Chemical Constituents and Pharmacological Properties of Dracaena cinnabari.
International Journal of Environmental Sciences (2025)
Link: https://theaspd.com/index.php/ijes/article/view/5140

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7. Pharmacological Effects of Dragon’s Blood from Dracaena Species

Zhang H, et al. Pharmacological effects of dragon’s blood from Dracaena species. (2024 review)
Link: https://www.sciencedirect.com/science/article/pii/S2590098624000253

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8. Antifungal Activity Against Candida albicans

Antifungal Properties of Dracaena cinnabari Resin Extracts Against Candida albicans.
Journal of Angiotherapy 
Link: https://www.publishing.emanresearch.org/Journal/MostReadAbstract/5566

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“These external studies are provided for educational purposes only and do not represent medical advice. Grandma’s House products are not intended to diagnose, treat, cure, or prevent any disease.”

Science Backed Benefits of Pearl Powder​

 

1. Pearl Powder—An Emerging Material for Biomedical Applications (Review)

Han, Q. et al. (2021)
Pearl Powder—An Emerging Material for Biomedical Applications: A Review
Link: https://pmc.ncbi.nlm.nih.gov/articles/PMC8197316/

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2. Hydrolyzed Conchiolin Protein for Skin Brightening

Yu, C. et al. (2023)
Hydrolyzed Conchiolin Protein (HCP) Extracted from Pearls Antagonizes ET-1 and α-MSH
Link: https://pubmed.ncbi.nlm.nih.gov/37108635/

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3. Pearl Extract for Melasma Support (Clinical Study)

Shen, Y. et al. (2025)
Margarita (Pearl) Extract Alleviates Melasma
(Insert link here once published)

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4. Human Trial – Antioxidant Effects of Pearl Powder

Chiu, H. et al. (2018)
Efficacy of Protein-Rich Pearl Powder on Antioxidant Status in a Randomized Placebo-Controlled Trial
Link: https://pubmed.ncbi.nlm.nih.gov/29434269/

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5. Nacre/Pearl Supplementation and Bone Protection

Shen, S. et al. (2022)
Protective Effect on Bone of Nacre Supplementation in Ovariectomized Rats
Link: https://pubmed.ncbi.nlm.nih.gov/36111203/

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6. Calcium Bioavailability of Nanonized Pearl Powder (Human Study)

Zhang, C. et al. (2010)
Calcium Bioavailability of Nanonized Pearl Powder for Adults
Link: https://pubmed.ncbi.nlm.nih.gov/20035429/

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7. Oral Nacre Extract — Anti-Aging Effects (Skin, Muscle, Lifespan) in Mice

Yamamoto, H.; Shimomura, N.; Hasegawa, Y. (2024)
Oral Administration of Nacre Extract from Pearl Oyster Shells Has Anti-Aging Effects on Skin and Muscle, and Extends the Lifespan in SAMP8 Mice. Pharmaceuticals, 17(6): 713.
Link: https://doi.org/10.3390/ph17060713 MDPI

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8. Water-Soluble Matrix (WSM) of Nanometer Pearl Powder Promotes Osteogenesis (Bone Formation in Cell Culture)

Xu, X. et al. (2025)
Effect of the water-soluble matrix of nanometer pearl powder (NPP WSM) on osteogenic differentiation and mineralization of hFOB1.19 osteoblast cells. (cell study)
Link: https://pmc.ncbi.nlm.nih.gov/articles/PMC12598726/ PMC

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9. Proteomic Characterization of Freshwater Pearl Powder — Bioactive Matrix Proteins

Luo, W. et al. (2022)
The proteomics of the freshwater pearl powder. (Study identifying matrix proteins, peptides, and bioactive constituents)
Link: https://www.sciencedirect.com/science/article/abs/pii/S1874391922001890 ScienceDirect

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10. Nacre / Pearl Powder Matrix Proteins — Review of Bioactivities (Osteogenic, Antioxidant, Anti-inflammatory, Wound Repair, etc.)

Pei, J.; Wang, Y.; Zou, X.; Ruan, H.; Tang, C.; Liao, J.; Si, G.; Sun, P. (2021)
Extraction, Purification, Bioactivities and Application of Matrix Proteins From Pearl Powder and Nacre Powder: A Review. Frontiers in Bioengineering and Biotechnology.
Link: https://doi.org/10.3389/fbioe.2021.649665 Frontiers

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11. Detoxification Potential — Heavy Metal Chelation & Organ Protection by Pearl Powder (In Vitro / In Vivo)

Nawabjan, S.A. et al. (2025)
Preparation, Characterization of Pearl Powder and Its In Vivo Detoxification Potential for Heavy Metals in Animal Models. (Antioxidant / detox study)
Link: https://www.sciencedirect.com/science/article/pii/S2772416624001244 ScienceDirect

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